SponsorBlock — YouTube Sponsor-Skipping Extension
~1 min read updated 25 April 2021

SponsorBlock skips the sponsor segments inside the YouTube videos you watch. The sponsor segments are marked by other users who already watched the video, and when you get to that timestamp, the video automatically jumps over the relevant part.
The extension is available in many environments, including Google Chrome, Mozilla Firefox, Microsoft Edge, Opera, and Android. Third-party builds for other devices are listed on their site too.
At the time of writing they reported a total of 1,282,217 sponsored segments blocked. Combined with a regular ad blocker, this gives you a near-complete ad block.